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1

SCAN database: facilitating integrative analyses of cytosine modification and expression QTL

Zhang, W., Gamazon, E. R., Zhang, X., Konkashbaev, A., Liu, C., Szilagyi, K. L., Dolan, M. E., Cox, N. J.

Journal:

Year:

2015

Language:

english

File:

PDF, 597 KB

english, 2015

2

A gene-based association method for mapping traits using reference transcriptome data

Gamazon, Eric R, Wheeler, Heather E, Shah, Kaanan P, Mozaffari, Sahar V, Aquino-Michaels, Keston, Carroll, Robert J, Eyler, Anne E, Denny, Joshua C, Nicolae, Dan L, Cox, Nancy J, Im, Hae Kyung

Journal:

Nature Genetics

Year:

2015

Language:

english

File:

PDF, 4.12 MB

english, 2015

3

Loci nominally associated with autism from genome-wide analysis show enrichment of brain expression quantitative trait loci but not lymphoblastoid cell line expression quantitative trait loci

Lea K Davis, Eric R Gamazon, Emily Kistner-Griffin, Judith A Badner, Chunyu Liu, Edwin H Cook, James S Sutcliffe, Nancy J Cox

Journal:

Molecular Autism

Year:

2012

Language:

english

File:

PDF, 602 KB

english, 2012

4

The impact of microRNA expression on cellular proliferation

Lenkala, Divya, LaCroix, Bonnie, Gamazon, Eric R., Geeleher, Paul, Im, Hae Kyung, Huang, R. Stephanie

Journal:

Year:

2014

Language:

english

File:

PDF, 386 KB

english, 2014

5

Gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the Helicobacter pylori INS-GAS mouse model of gastric carcinogenesis

Lertpiriyapong, K., Whary, M. T., Muthupalani, S., Lofgren, J. L., Gamazon, E. R., Feng, Y., Ge, Z., Wang, T. C., Fox, J. G.

Journal:

Year:

2014

Language:

english

File:

PDF, 7.10 MB

english, 2014

6

Consistency in large pharmacogenomic studies

Geeleher, Paul, Gamazon, Eric R., Seoighe, Cathal, Cox, Nancy J., Huang, R. Stephanie

Journal:

Year:

2016

Language:

english

File:

PDF, 268 KB

english, 2016

7

MULTI-TISSUE TRANSCRIPTOME ANALYSIS REVEALS GENETIC MECHANISMS OF NEUROPSYCHIATRIC TRAITS

Derks, Eske, Gamazon, Eric, Zwinderman, Aeilko, Cox, Nancy, Denys, Damiaan

Journal:

European Neuropsychopharmacology

Year:

2019

Language:

english

File:

PDF, 35 KB

english, 2019

8

A gene co-expression network-based analysis of multiple brain tissues reveals novel genes and molecular pathways underlying major depression

Gerring, Zachary F., Gamazon, Eric R., Derks, Eske M., Myers, Amanda J.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.87 MB

english, 2019

9

Inferred divergent gene regulation in archaic hominins reveals potential phenotypic differences

Colbran, Laura L., Gamazon, Eric R., Zhou, Dan, Evans, Patrick, Cox, Nancy J., Capra, John A.

Journal:

Nature Ecology & Evolution

Year:

2019

Language:

english

File:

PDF, 1.42 MB

english, 2019

10

Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals

J. E. Below, E. R. Gamazon, J. V. Morrison, A. Konkashbaev, A. Pluzhnikov, P. M. McKeigue, E. J. Parra, S. C. Elbein, D. M. Hallman, D. L. Nicolae, G. I. Bell, M. Cruz, N. J. Cox, C. L. Hanis

Journal:

Year:

2011

Language:

english

File:

PDF, 273 KB

english, 2011

11

The Missing Association: Sequencing-Based Discovery of Novel SNPs in VKORC1 and CYP2C9 That Affect Warfarin Dose in African Americans

Perera, M A, Gamazon, E, Cavallari, L H, Patel, S R, Poindexter, S, Kittles, R A, Nicolae, D, Cox, N J

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 244 KB

english, 2011

12

Identification of novel germline polymorphisms governing capecitabine sensitivity

Peter H. O'Donnell, Amy L. Stark, Eric R. Gamazon, Heather E. Wheeler, Bridget E. McIlwee, Lidija Gorsic, Hae Kyung Im, R. Stephanie Huang, Nancy J. Cox, M. Eileen Dolan

Journal:

Year:

2012

Language:

english

File:

PDF, 1.56 MB

english, 2012

13

On Sharing Quantitative Trait GWAS Results in an Era of Multiple-omics Data and the Limits of Genomic Privacy

Hae Kyung Im, Eric R. Gamazon, Dan L. Nicolae, Nancy J. Cox

Journal:

The American Journal of Human Genetics

Year:

2012

Language:

english

File:

PDF, 341 KB

english, 2012

14

Genetic Architecture of MicroRNA Expression: Implications for the Transcriptome and Complex Traits

Eric R. Gamazon, Dana Ziliak, Hae Kyung Im, Bonnie LaCroix, Danny S. Park, Nancy J. Cox, R. Stephanie Huang

Journal:

The American Journal of Human Genetics

Year:

2012

Language:

english

File:

PDF, 968 KB

english, 2012

15

Identification of a genetic variant associated with treatment outcome in ovarian cancer: the potential role of cholesterol metabolism as a determinant of response to chemotherapy

Georgia Chenevix-Trench, Yi Lu, Sharon Johnatty, Eric Gamazon, Jonathan Beesley, Xiaoqing Chen, Bo Gao, Paul Harnett, R Stephanie Huang, Evelyn Despierre, Florian Heitz, Estrid Hogdall, Claus Hogdall,

Journal:

Hereditary Cancer in Clinical Practice

Year:

2012

Language:

english

File:

PDF, 81 KB

english, 2012

16

Response to Knoppers et al.

Hae Kyung Im, Eric R. Gamazon, Dan L. Nicolae, Nancy J. Cox

Journal:

The American Journal of Human Genetics

Year:

2012

Language:

english

File:

PDF, 31 KB

english, 2012

17

Genetic Risk Factors for Type 2 Diabetes: A Trans-Regulatory Genetic Architecture?

Steven C. Elbein, Eric R. Gamazon, Swapan K. Das, Neda Rasouli, Philip A. Kern, Nancy J. Cox

Journal:

The American Journal of Human Genetics

Year:

2012

Language:

english

File:

PDF, 620 KB

english, 2012

18

An Exponential Combination Procedure for Set-Based Association Tests in Sequencing Studies

Lin S. Chen, Li Hsu, Eric R. Gamazon, Nancy J. Cox, Dan L. Nicolae

Journal:

The American Journal of Human Genetics

Year:

2012

Language:

english

File:

PDF, 894 KB

english, 2012

19

Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers

Dana Ziliak, Peter H. O'donnell, Hae Kyung Im, Eric R. Gamazon, Peixian Chen, Shannon Delaney, Sunita Shukla, Soma Das, Nancy J. Cox, Everett E. Vokes, Ezra E.W. Cohen, M. Eileen Dolan, R. Stephanie H

Journal:

Translational Research

Year:

2011

Language:

english

File:

PDF, 308 KB

english, 2011

20

Genome-wide association study of obsessive-compulsive disorder

Stewart, S E, Yu, D, Scharf, J M, Neale, B M, Fagerness, J A, Mathews, C A, Arnold, P D, Evans, P D, Gamazon, E R, Osiecki, L, McGrath, L, Haddad, S, Crane, J, Hezel, D, Illman, C, Mayerfeld, C, Konka

Journal:

Molecular Psychiatry

Year:

2013

Language:

english

File:

PDF, 779 KB

english, 2013

21

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study

Perera, Minoli A, Cavallari, Larisa H, Limdi, Nita A, Gamazon, Eric R, Konkashbaev, Anuar, Daneshjou, Roxana, Pluzhnikov, Anna, Crawford, Dana C, Wang, Jelai, Liu, Nianjun, Tatonetti, Nicholas, Bourge

Journal:

Year:

2013

Language:

english

File:

PDF, 759 KB

english, 2013

22

Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants

Gamazon, E R, Badner, J A, Cheng, L, Zhang, C, Zhang, D, Cox, N J, Gershon, E S, Kelsoe, J R, Greenwood, T A, Nievergelt, C M, Chen, C, McKinney, R, Shilling, P D, Schork, N J, Smith, E N, Bloss, C S,

Journal:

Molecular Psychiatry

Year:

2013

Language:

english

File:

PDF, 498 KB

english, 2013

23

A genome-wide integrative study of microRNAs in human liver

Eric R Gamazon, Federico Innocenti, Rongrong Wei, Libo Wang, Min Zhang…

Journal:

Year:

2013

Language:

english

File:

PDF, 442 KB

english, 2013

24

The regulatory effect of miRNAs is a heritable genetic trait in humans

Paul Geeleher, R Stephanie Huang, Eric R Gamazon, Aaron Golden…

Journal:

Year:

2012

Language:

english

File:

PDF, 398 KB

english, 2012

25

Copy number polymorphisms and anticancer pharmacogenomics

Eric R Gamazon, R Stephanie Huang, M Eileen Dolan, Nancy J Cox

Journal:

Year:

2011

Language:

english

File:

PDF, 1.88 MB

english, 2011

26

Ethnicity-specific pharmacogenetics: the case of warfarin in African Americans

Hernandez, W, Gamazon, E R, Aquino-Michaels, K, Patel, S, O'Brien, T J, Harralson, A F, Kittles, R A, Barbour, A, Tuck, M, McIntosh, S D, Douglas, J N, Nicolae, D, Cavallari, L H, Perera, M A

Journal:

The Pharmacogenomics Journal

Year:

2014

Language:

english

File:

PDF, 351 KB

english, 2014

27

A Genome-wide Association Study of Early-Onset Breast Cancer Identifies PFKM as a Novel Breast Cancer Gene and Supports a Common Genetic Spectrum for Breast Cancer at Any Age

Ahsan, H., Halpern, J., Kibriya, M. G., Pierce, B. L., Tong, L., Gamazon, E., McGuire, V., Felberg, A., Shi, J., Jasmine, F., Roy, S., Brutus, R., Argos, M., Melkonian, S., Chang-Claude, J., Andrulis,

Journal:

Cancer Epidemiology Biomarkers & Prevention

Year:

2014

Language:

english

File:

PDF, 503 KB

english, 2014

28

Genome-wide association study of Tourette's syndrome

Scharf, J M, Yu, D, Mathews, C A, Neale, B M, Stewart, S E, Fagerness, J A, Evans, P, Gamazon, E, Edlund, C K, Service, S K, Tikhomirov, A, Osiecki, L, Illmann, C, Pluzhnikov, A, Konkashbaev, A, Davis

Journal:

Molecular Psychiatry

Year:

2013

Language:

english

File:

PDF, 605 KB

english, 2013

29

Obesity-associated variants within FTO form long-range functional connections with IRX3

Smemo, Scott, Tena, Juan J., Kim, Kyoung-Han, Gamazon, Eric R., Sakabe, Noboru J., Gómez-Marín, Carlos, Aneas, Ivy, Credidio, Flavia L., Sobreira, Débora R., Wasserman, Nora F., Lee, Ju Hee, Puviindra

Journal:

Year:

2014

Language:

english

File:

PDF, 6.95 MB

english, 2014

30

Genetic variation associated with euphorigenic effects of d-amphetamine is associated with diminished risk for schizophrenia and attention deficit hyperactivity disorder

Hart, A. B., Gamazon, E. R., Engelhardt, B. E., Sklar, P., Kahler, A. K., Hultman, C. M., Sullivan, P. F., Neale, B. M., Faraone, S. V., de Wit, H., Cox, N. J., Palmer, A. A., Anney, R., Asherson, P.,

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 912 KB

english, 2014

31

Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death

Ko, D. C., Gamazon, E. R., Shukla, K. P., Pfuetzner, R. A., Whittington, D., Holden, T. D., Brittnacher, M. J., Fong, C., Radey, M., Ogohara, C., Stark, A. L., Akey, J. M., Dolan, M. E., Wurfel, M. M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2012

Language:

english

File:

PDF, 1.41 MB

english, 2012

32

Genetic factors affecting gene transcription and catalytic activity of UDP-glucuronosyltransferases in human liver

Liu, W., Ramirez, J., Gamazon, E. R., Mirkov, S., Chen, P., Wu, K., Sun, C., Cox, N. J., Cook, E., Das, S., Ratain, M. J.

Journal:

Human Molecular Genetics

Year:

2014

Language:

english

File:

PDF, 395 KB

english, 2014

33

Genomics of alternative splicing: evolution, development and pathophysiology

Gamazon, Eric R., Stranger, Barbara E.

Journal:

Year:

2014

Language:

english

File:

PDF, 353 KB

english, 2014

34

Integrative analyses of genetic variation, epigenetic regulation, and the transcriptome to elucidate the biology of platinum sensitivity

LaCroix, Bonnie, Gamazon, Eric R, Lenkala, Divya, Im, Hae, Geeleher, Paul, Ziliak, Dana, Cox, Nancy J, Huang, Rong

Journal:

Year:

2014

Language:

english

File:

PDF, 369 KB

english, 2014

35

Genetic association signal near NTN 4 in Tourette syndrome

Paschou, Peristera, Yu, Dongmei, Gerber, Gloria, Evans, Patrick, Tsetsos, Fotis, Davis, Lea K., Karagiannidis, Iordanis, Chaponis, Jonathan, Gamazon, Eric, Mueller-Vahl, Kirsten, Stuhrmann, Manfred, S

Journal:

Annals of Neurology

Year:

2014

Language:

english

File:

PDF, 93 KB

english, 2014

36

Discovery and Functional Assessment of Gene Variants in the Vascular Endothelial Growth Factor Pathway

Paré-Brunet, Laia, Glubb, Dylan, Evans, Patrick, Berenguer-Llergo, Antoni, Etheridge, Amy S., Skol, Andrew D., Di Rienzo, Anna, Duan, Shiwei, Gamazon, Eric R., Innocenti, Federico

Journal:

Year:

2014

Language:

english

File:

PDF, 334 KB

english, 2014

37

Integrating Cell-Based and Clinical Genome-Wide Studies to Identify Genetic Variants Contributing to Treatment Failure in Neuroblastoma Patients

Pinto, N, Gamazon, E R, Antao, N, Myers, J, Stark, A L, Konkashbaev, A, Im, H K, Diskin, S J, London, W B, Ludeman, S M, Maris, J M, Cox, N J, Cohn, S L, Dolan, M E

Journal:

Clinical Pharmacology & Therapeutics

Year:

2014

Language:

english

File:

PDF, 266 KB

english, 2014

38

Genome-wide discovery of genetic variants affecting tamoxifen sensitivity and their clinical and functional validation

Weng, L., Ziliak, D., Im, H. K., Gamazon, E. R., Philips, S., Nguyen, A. T., Desta, Z., Skaar, T. C., Flockhart, D. A., Huang, R. S.

Journal:

Annals of Oncology

Year:

2013

Language:

english

File:

PDF, 263 KB

english, 2013

39

Structural Architecture of SNP Effects on Complex Traits

Gamazon, Eric R., Cox, Nancy J., Davis, Lea K.

Journal:

The American Journal of Human Genetics

Year:

2014

Language:

english

File:

PDF, 1.19 MB

english, 2014

40

Translating pharmacogenomics discoveries into the clinic: an implementation framework

R Stephanie Huang,Eric R Gamazon

Journal:

Genome Medicine

Year:

2013

Language:

english

File:

PDF, 112 KB

english, 2013

41

Cross-Tissue and Tissue-Specific eQTLs: Partitioning the Heritability of a Complex Trait

Torres, Jason M., Gamazon, Eric R., Parra, Esteban J., Below, Jennifer E., Valladares-Salgado, Adan, Wacher, Niels, Cruz, Miguel, Hanis, Craig L., Cox, Nancy J.

Journal:

The American Journal of Human Genetics

Year:

2014

Language:

english

File:

PDF, 869 KB

english, 2014

42

Poly-Omic Prediction of Complex Traits: OmicKriging

Wheeler, Heather E., Aquino-Michaels, Keston, Gamazon, Eric R., Trubetskoy, Vassily V., Dolan, M. Eileen, Huang, R. Stephanie, Cox, Nancy J., Im, Hae Kyung

Journal:

Genetic Epidemiology

Year:

2014

Language:

english

File:

PDF, 729 KB

english, 2014

43

Identification of a Variant in KDR Associated with Serum VEGFR2 and Pharmacodynamics of Pazopanib

Maitland, M. L., Xu, C.-F., Cheng, Y.-C., Kistner-Griffin, E., Ryan, K. A., Karrison, T. G., Das, S., Torgerson, D., Gamazon, E. R., Thomeas, V., Levine, M. R., Wilson, P. A., Bing, N., Liu, Y., Cardo

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 545 KB

english, 2015

44

Genome-wide Interrogation of Longitudinal FEV 1 in Children with Asthma

Wu, Kehua, Gamazon, Eric R., Im, Hae Kyung, Geeleher, Paul, White, Steven R., Solway, Julian, Clemmer, George L., Weiss, Scott T., Tantisira, Kelan G., Cox, Nancy J., Ratain, Mark J., Huang, R. Stepha

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2014

Language:

english

File:

PDF, 878 KB

english, 2014

45

Platinum Sensitivity-Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients

Huang, R. S., Johnatty, S. E., Gamazon, E. R., Im, H. K., Ziliak, D., Duan, S., Zhang, W., Kistner, E. O., Chen, P., Beesley, J., Mi, S., O'Donnell, P. H., Fraiman, Y. S., Das, S., Cox, N. J., Lu, Y.,

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 3.49 MB

english, 2011

46

Genetic Variation That Predicts Platinum Sensitivity Reveals the Role of miR-193b* in Chemotherapeutic Susceptibility

Ziliak, D., Gamazon, E. R., LaCroix, B., Kyung Im, H., Wen, Y., Huang, R. S.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.03 MB

english, 2012

47

Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette’s Syndrome and OCD

Yu, Dongmei, Mathews, Carol A., Scharf, Jeremiah M., Neale, Benjamin M., Davis, Lea K., Gamazon, Eric R., Derks, Eske M., Evans, Patrick, Edlund, Christopher K., Crane, Jacquelyn, Fagerness, Jesen A.,

Journal:

American Journal of Psychiatry

Year:

2015

Language:

english

File:

PDF, 1.22 MB

english, 2015

48

Chemotherapeutic drug susceptibility associated SNPs are enriched in expression quantitative trait loci

Eric R. Gamazon, R. Stephanie Huang, Nancy J. Cox, M. Eileen Dolan and Janet D. Rowley

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.38 MB

english, 2010

49

MicroRNA biogenesis and cellular proliferation

Lenkala, Divya, Gamazon, Eric R., LaCroix, Bonnie, Im, Hae Kyung, Huang, R.Stephanie

Journal:

Translational Research

Year:

2015

Language:

english

File:

PDF, 478 KB

english, 2015

50

Chemotherapeutic drug susceptibility associated SNPs are enriched in expression quantitative trait loci

Gamazon, E. R., Huang, R. S., Cox, N. J., Dolan, M. E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 428 KB

english, 2010

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